Q. 3

[McatCrusher]

i read the answer and it made so much sense, but when i tried to find the same information in the passage(P3), i could not. I didnt quite underestand how i should extract those information from the passage?

[Dr. Ferdinand]

Background: enzymes often let you know their activity by their name. Peptidyl transferase transfers one amino acid to another thus creating a peptide bond: the continuation of this process creates and elongates a protein.

Here is paragraph 3:

The consequence of release factor recognition of a termination codon is to alter the peptidyl transferase center on the large ribosomal subunit so that it can accept water as the attacking nucleophile rather than requiring the normal substrate, aminoacyl-tRNA.

Translation of all the above: peptidyl transferase is important for 2 things: (1) peptide bonds and (2) when modified, peptidyl transferase can permit water to attack. So both (1) and (2) will not occur if peptidyl transferase activity is inhibited.

[admin]

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